Comparison of intent-to-treat analysis strategies for pre-post studies with loss to follow-up
نویسندگان
چکیده
منابع مشابه
Intent-to-treat analysis for longitudinal studies with drop-outs.
We consider intent-to-treat (IT) analysis of clinical trials involving longitudinal data subject to drop-out. Common methods, such as Last Observation Carried Forward imputation or incomplete-data methods based on models that assume random dropout, have serious drawbacks in the IT setting. We propose a method that involves multiple imputation of the missing values following drop-out based on an...
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15 صفحه اولLoss to follow-up
Why do these situations make a difference? Because in each situation, those lost to follow-up often have a different prognosis than those who complete the study. For example, patients who receive treatment for cervical myelopathy may not return for follow-up because they became asymptomatic and felt no need to return to see the surgeon. Conversely, some patients may not return because they had ...
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هدف از این تحقیق بررسی برخی عوامل ادراکی واحساسی یعنی استفاده از شیوه های یادگیری زبان ، انگیزه ها ونگرش نسبت به زبان انگلیسی در رابطه با زمینه زبانی زبان آموزان می باشد. هدف بررسی این نکته بود که آیا اختلافی چشمگیر میان زبان آموزان دو زبانه و تک زبانه در میزان استفاده از شیوه های یادگیری زبان ، انگیزه ها نگرش و سطح مهارت زبانی وجود دارد. همچنین سعی شد تا بهترین و موثرترین عوامل پیش بینی کننده ...
15 صفحه اولLoss to follow-up matters.
Survival analysis of joint replacement relies on the assumption that surgical procedures in patients lost to follow-up have the same chance of failing as those in patients who continue to be assessed. Our study questions that assumption. During the 16-year follow-up of 2268 patients who had received total hip replacements 142 (6%) were lost to follow-up. The cumulative loss at 15 years was 20%....
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ژورنال
عنوان ژورنال: Contemporary Clinical Trials Communications
سال: 2018
ISSN: 2451-8654
DOI: 10.1016/j.conctc.2018.05.008