Comparison of Gene Delivery Techniques for Therapeutic Angiogenesis
نویسندگان
چکیده
منابع مشابه
Comparison of gene delivery techniques for therapeutic angiogenesis ultrasound-mediated destruction of carrier microbubbles versus direct intramuscular injection.
OBJECTIVES This study was designed to compare the efficacy of angiogenic gene delivery by ultrasound-mediated (UM) destruction of intravenous carrier microbubbles to direct intramuscular (IM) injections. BACKGROUND Current trials of gene therapy for angiogenesis remain limited by suboptimal, invasive delivery techniques. METHODS Hind-limb ischemia was produced by iliac artery ligation in 99...
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چکیده ندارد.
15 صفحه اولDelivery strategies to achieve therapeutic myocardial angiogenesis.
The use of recombinant genes or growth factors to enhance myocardial collateral blood vessel function may represent a new approach to the treatment of cardiovascular disease. Proof of concept has been demonstrated in animal models of myocardial ischemia, and clinical trials are underway. Currently, it is unknown which is the safest and most effective delivery strategy to induce clinically impor...
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Introduction: In the treatment of breast cancer, breast conserving surgery (BCS) and whole breast irradiation is a usual technique. The influence of lumpectomy boost following breast radiotherapy is apparent, but there are different delivery methods. This work intended to compare the dosimetric parameters of electron beams and photon beams for boosting irradiation in breast can...
متن کاملNonviral delivery of genetic medicine for therapeutic angiogenesis.
Genetic medicines that induce angiogenesis represent a promising strategy for the treatment of ischemic diseases. Many types of nonviral delivery systems have been tested as therapeutic angiogenesis agents. However, their delivery efficiency, and consequently therapeutic efficacy, remains to be further improved, as few of these technologies are being used in clinical applications. This article ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2009
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.07.023