Comparison of Efficacy between Topical Luliconazole and Topical Clotrimazole in the Treatment of Tinea Corporis and Tinea Cruris

Background: The prevalence of Tinea Corporis and Cruris infections are increasing in Bangladesh due to its tropical climate, along with low socio-economic conditions. In treatment these infections, Clotrimazole has been used for a long time. But Luliconazole is newer drug which offering more efficacy tolerability short duration treatment. Methods: An observational comparative study was directed assess the topical over among 175 OPD patients Department Dermatology Venereology, Sylhet MAG Osmani Medical College Hospital. patient’s score followed up by using 4-point scale Global Assessment Score. Results: mean age Group A 33.94±13.95 years B 32.64±13.15 male were predominant both groups (65.2% 66.3%). corporis prevalent 70.9%). number infection lesion 2.35±1.12 2.30±1.13. 3.33±5.98 months 2.38±3.36 respective groups. Papules found 61.4% 51.4% respectively. Based on GAS, at end first week treatment, significant difference distributions case erythema papules. At pruritus scaling. 4 weeks after pruritus, scaling (p<0.005). GAS 6.95±1.05 baseline, gradually decreased 3.16±1.27, 1.02±1.01 0.42±1.32 first, second third visit. On other side, B, from 7.21±1.27 3.87±1.28, 1.33±1.37 1.23±2.01 Complete cure observed (32.6%) compared (12.8%) one whereas no response (55.8%) (28.1%). These changes distribution (p=0.004). visit, complete 89.9% 77.9% B. reached level significance (p=0.031). last only 2.2% completely cured 16.3% developed relapse disease, also significantly (p=0.001). Conclusion: be superior terms course, less failure that Clotrimazole.