COMPARISON OF EFFECTS OF PROTAMINE AND POLYBRENE, WITH SPECIAL EMPHASIS ON THE FACTOR VIII (ANTI-HEMOPHILIC GLOBULIN) DEFICIENCY INDUCED*
نویسندگان
چکیده
منابع مشابه
Comparison of effects of protamine and polybrene, with special emphasis on the factor VIII (antihemophilic globulin) deficiency induced.
Successful achievement of extracorporeal circulation requires that blood coagulability be temporarily interrupted during perfusion and afterward restored to normal. Heparin is accepted as the drug of choice in rendering the blood incoagulable, but there are two drugs, protamine and Polybrene (hexadimethrine bromide), available for effective in vivo neutralization of heparin, and controversy exi...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1961
ISSN: 0021-9738
DOI: 10.1172/jci104373