Comparison of Different Phenotypic Tests for the Detection of Metallo-B-Lactamase (MBL) Producing Pseudomonas aeruginosa
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چکیده
منابع مشابه
Comparison of Different Phenotypic Tests for the Detection of Metallo-B-Lactamase (MBL) Producing Pseudomonas aeruginosa
MBL production has been increasingly reported among Pseudomonas aeruginosa, which is an important nosocomial multidrug resistant pathogen. 2,3 Metallo beta lactamase (MBL) belongs to Ambler class B enzymes. With the help of divalent cation zinc as cofactor for enzymatic activity, they hydrolyze carbapenem as-well-as other blactam antibiotics. The substrate spectrum of this enzyme is quite broad...
متن کاملPhenotypic Detection Of Metallo-beta-lactamase Producing Pseudomonas aeruginosa Strains Isolated From Burned Patients
Background and Objective: Metallo-beta-lactamase (MBL)-mediated resistance is an emerging threat in hospital isolates of Pseudomonas aeruginosa. There is not enough information from Iran regarding the prevalence and the screening methods for such enzymes. The present study was undertaken to detect Metallo betalactamase in strains of P. aeruginosa isolated from burned patien...
متن کاملAn evaluation of four different phenotypic techniques for detection of metallo-beta-lactamase producing Pseudomonas aeruginosa.
PURPOSE The present study was undertaken to detect metallo-beta-lactamase (MBL) in nosocomial isolates of Pseudomonas aeruginosa by four different phenotypic methods. METHODS Ninety-one consecutive P. aeruginosa isolates were subjected to susceptibility testing by disc-diffusion assay and Vitek 2. Imipenem resistance was determined by three different methods (disc-diffusion, Vitek 2 and E tes...
متن کاملEvaluation of phenotypic tests for the detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a low prevalence country.
OBJECTIVES To evaluate four phenotypic tests for the detection of metallo-beta-lactamase (MBL) production in Pseudomonas aeruginosa in a low MBL prevalence setting. METHODS Sixty clinical isolates of P. aeruginosa resistant to imipenem and/or meropenem and seven MBL-positive control strains were examined by: (i) MBL Etest; (ii) combined imipenem discs supplemented with EDTA (IPM-EDTA); (iii) ...
متن کاملPhenotypic Detection of Metallo Beta Lactamase Producing Pseudomonas Aeruginosa in Wounds
Pseudomonas aeruginosa, an important opportunistic pathogen causing a wide range of acute and chronic infections.The present study was undertaken to detect the Metallo β lactamase in isolated of Pseudomonas aeruginosa which was isolated from wound infection and evaluated their susceptibility patterns.The presence of the MBL enzyme was detected by phenotypic confirmatiory tests are IMIPENEM-EDTA...
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ژورنال
عنوان ژورنال: International Journal of Current Microbiology and Applied Sciences
سال: 2017
ISSN: 2319-7692,2319-7706
DOI: 10.20546/ijcmas.2017.610.378