Comparative MO-QSAR studies in various species including man
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منابع مشابه
Comparative MO-QSAR studies in various species including man.
In the present study it is demonstrated that MO-QSARs (quantitative structure activity relationships based on calculated molecular orbital substrate characteristics) of cytochrome P450-catalysed biotransformation of benzene derivatives obtained in previous studies for Wistar rats, can be extrapolated to other species, including man. First, it was demonstrated that the regioselectivity of the in...
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A mixed toxoid consisting of HR1 and HR2 toxoids derived from Habu (Trimeresurus flavoviridis) venom was examined for immunogenicity in guinea pigs, rabbits, monkeys and human beings. The toxoid produced both anti-HR1 and anti-HR2 in various animals. The immunogenicity of the toxoid was superior to a crude toxoid in both guinea pigs and monkeys. Immunized monkeys showing circulating antitoxin p...
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Serine esterases were detected in the granules of mucosal mast cells from rat, mouse, sheep, and man. Successful demonstration of enzyme activity required brief fixation (6 h) of tissues in 4% paraformaldehyde. Staining with naphthol AS-D chloroacetate produced an intense red reaction product in intraepithelial mucosal mast cells (globule leucocytes) and mucosal mast cells within the lamina pro...
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ژورنال
عنوان ژورنال: Chemico-Biological Interactions
سال: 1996
ISSN: 0009-2797
DOI: 10.1016/0009-2797(96)03699-x