Comparative Metagenomics with Metabolic Reconstruction
نویسندگان
چکیده
منابع مشابه
Comparative Analysis of Metabolic Pathways in Metagenomics
Metagenomics is the study of organismal DNA sequences obtained from an environmental sample. Metagenomic studies often compare samples taken from different locations (e.g., the human gut, lakes and oceans, soil) to assess significant differences in taxonomic makeup, genetic makeup, or function. Differences in function can be characterized by measuring the differential abundance of metabolic pat...
متن کاملComparative Metagenomics by Cross-assembly
[1] Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud university medical centre, Nijmegen, The Netherlands. [2] Department of Marine Biology, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. [3] Computational Science Research Center, [4] Department of Mathematics, and [5] Department of Biology, San Diego St...
متن کاملComparative metagenomics of microbial communities.
The species complexity of microbial communities and challenges in culturing representative isolates make it difficult to obtain assembled genomes. Here we characterize and compare the metabolic capabilities of terrestrial and marine microbial communities using largely unassembled sequence data obtained by shotgun sequencing DNA isolated from the various environments. Quantitative gene content a...
متن کاملToward Accurate and Quantitative Comparative Metagenomics
Shotgun metagenomics and computational analysis are used to compare the taxonomic and functional profiles of microbial communities. Leveraging this approach to understand roles of microbes in human biology and other environments requires quantitative data summaries whose values are comparable across samples and studies. Comparability is currently hampered by the use of abundance statistics that...
متن کاملSimka: large scale de novo comparative metagenomics
Comment citer ce document : Benoit, G. (Auteur de correspondance), Peterlongo, P., Mariadassou, M., Drezen, E., Schbath, S., Lavenier, D., Lemaitre, C. (2017). Simka: large scale de novo comparative metagenomics. In: JOBIM 2017 LILLE (p. 3-5). Presented at JOBIM 2017 Journées Ouvertes Biologie Informatique Mathématiques, Lille, FRA (2017-07-03 2017-07-06). Simka: large scale de novo comparative...
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ژورنال
عنوان ژورنال: MOJ Proteomics & Bioinformatics
سال: 2015
ISSN: 2374-6920
DOI: 10.15406/mojpb.2015.02.00049