COMPARATIVE EVALUATION OF GINGIVAL CREVICULAR FLUID AND SALIVARY SCLEROSTIN LEVELS IN CHRONIC PERIODONTITIS PATIENTS WITH OR WITHOUT TYPE 2 DIABETES MELLITUS: A CROSS-SECTIONAL STUDY

Introduction: Chronic Periodontitis is an infectious disease resulting in inflammation within the supporting tissues of teeth leading to progressive attachment and bone loss. Biochemical mediators oral fluids like saliva gingival crevicular fluid (GCF) are highly beneficial determination current periodontal status. Aim & objective: A comparative evaluation GCF salivary sclerostin levels chronic periodontitis patients with or without type 2 diabetes mellitus Methodology: total 36 subjects age group 30-60 years were categorised into three groups. Group I (Healthy individuals) II (chronic patients) III mellitus). During first visit clinical parameters Plaque index, Gingival Probing pocket depth Clinical level recorded. On subsequent day samples collected subjected for laboratory analysis using ELISA kit. Results tabulated statistical analysis. Discussion: The differences Sclerostin Saliva between groups not statistically significant (P = 0.089). =0.000). Conclusion: a promising diagnostic prognostic biomarker diseases.