Comparative Effects of Pyrroloquinoline Quinone (PQQ) and Resveratrol (RSV) on Mitochondriogenesis in Mice
نویسندگان
چکیده
منابع مشابه
The pyrroloquinoline quinone (PQQ)-containing quinoprotein dehydrogenases.
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Hitherto unknown effects of Pyrroloquinoline quinone (PQQ) in 6-n-propyl-2-thiouracil (PTU)induced oxidative stress and lipid peroxidation were investigated in adult mice. Animals received either PTU (0.05% in drinking water) alone for 5 weeks or PTU + three different concentrations of PQQ, after which alterations in tissue lipid peroxidation (LPO) and in enzymatic activities of superoxide dism...
متن کاملA subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt in rats.
A subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt was performed in rats. Sprague-Dawley rats were randomly divided into four groups (10 rats/sex/group) and administered with PQQ disodium salt at doses of 0 (control), 100, 200 and 400 mg/kg bw/day by gavage for 13 weeks. Daily clinical observations and weekly measurement of body weights and food consumption were co...
متن کاملThe Life History of Pyrroloquinoline Quinone (PQQ): A Versatile Molecule with Novel Impacts on Living Systems
Pyrroloquinoline quinone (4, 5-dihydro(4), 5-dioxo(1) H-pyrroloquinoline-2,7, 9 tricarboxylic acid) being a three ortho cyclic quinone substitutes the role of a redox-cofactor for various bacterial dehydrogenases such as methanol, ethanol and glucose dehydrogenases [1-6] also termed as methotaxin [7]. PQQ structure prediction shows that it has been originated from tyrosine and Glutamic-acid [8]...
متن کاملProduction and Radioprotective Effects of Pyrroloquinoline Quinone
Pyrroloquinoline quinone (PQQ) was produced by fermentation of the Methylovorus sp. MP688 strain and purified by ion-exchange chromatography, crystallization and recrystallization. The yield of PQQ reached approximately 125 mg/L and highly pure PQQ was obtained. To determine the optimum dose of PQQ for radioprotection, three doses (2 mg/kg, 4 mg/kg, 8 mg/kg) of PQQ were orally administrated to ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2021
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2021.35.s1.05142