Comparative Effects of Metoclopramide and Bethanechol on Lower Esophageal Sphincter Pressure in Reflux Patients
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چکیده
منابع مشابه
Upper esophageal sphincter during transient lower esophageal sphincter relaxation: effects of reflux content and posture.
Although some studies show that the upper esophageal sphincter (UES) contracts during transient lower esophageal sphincter relaxation (TLESR), others show that it relaxes. We hypothesized that the posture of the subject and constituents of gastroesophageal reflux (GER) may determine the type of UES response during the TLESR. High-resolution manometry and esophageal pH/impedance recording were p...
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3 McCallum RW, Kline MM, Curry N, Sturdevant RAL. Comparative efforts of metoclopramide and bethanechol on lower esophageal sphincter pressure in reflux patients. Gastroenterology 1975;68:1 114-8. McCallum RW, Berkowitz DM. The frequency of delayed gastric emptying in patients with gastroesophageal reflux and its response to metoclopramide and bethanechol. Gastroenterology 1978 ;74:1135. Gugler...
متن کاملLeg raise increases pressure in lower and upper esophageal sphincter among patients with gastroesophageal reflux disease.
The purpose of this study was to determine the relation between posturally increased intra-abdominal pressure and lower/upper esophageal sphincter pressure changes in patients with gastroesophageal reflux disease. We used high resolution manometry to measure pressure changes in lower and upper esophageal sphincter during bilateral leg rise. We also examined whether the rate of lower and upper e...
متن کاملSingle and combined effects of atropine and metoclopramide on the lower oesophageal sphincter pressure.
The effects of atropine and metoclopramide on the lower oesophageal sphincter pressure (LOSP) were studied in 12 healthy volunteers using oesophageal pressure transducers. Atropine decreased LOSP significantly at 5 min after i.v. injection (P less than 0.005) and this change was sustained for 60 min. Metoclopramide increased LOSP significantly at 3 min after administration i.v. (P less than 0.0...
متن کاملEffects of dexmedetomidine and propofol on lower esophageal sphincter and gastroesophageal pressure gradient in healthy volunteers.
BACKGROUND Many anesthetics reduce lower esophageal sphincter pressure (LESP). Reduced pressure and consequent reduction in the gastroesophageal pressure gradient (GEPG) thus promotes gastroesophageal reflux and may contribute to aspiration pneumonia and associated morbidity. Therefore, the authors compared LESP and GEPG during dexmedetomidine and propofol sedation. METHODS Using a randomized...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1975
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(75)80223-x