منابع مشابه
Comparative biochemical and biophysical studies on rat brain synaptosomes.
1. Introduction tosomal fractions was also checked by electron microscopy. Synaptosome isolation methods should meet two principal but contradicting requirements: The fraction should be enriched as much as possible in synap tosomes, while the amount of time used during the isolation process should be as short as possible. The conditions of synaptosomal preparation and the duration of each step ...
متن کاملComparative Biochemical Studies of Adriamycin and Daunomycin in Leukemic Cells1
Adriamycin (AM) and daunomycin (DM) were compared as inhibitors of nucleic acid and protein biosynthesis in LI 210 leukemic cells. In vivo, both antibiotics markedly inhibited, without significant difference, the incorporation of the labeled precursors into DNA and RNA. In vitro, at a concentration of 5 or lOjUg/ml, DM was significantly more effective than AM in inhibiting DNA and RNA synthesis...
متن کاملComparative biochemical studies of adriamycin and daunomycin in leukemic cells.
Adriamycin (AM) and daunomycin (DM) were compared as inhibitors of nucleic acid and protein biosynthesis in LI 210 leukemic cells. In vivo, both antibiotics markedly inhibited, without significant difference, the incorporation of the labeled precursors into DNA and RNA. In vitro, at a concentration of 5 or lOjUg/ml, DM was significantly more effective than AM in inhibiting DNA and RNA synthesis...
متن کاملBiochemical Studies on Shock
During and following the production of shock by hemorrhage in the normal, suprareno-demedullated, and suprarenalectomized rat, the following significant changes in amino acid and carbohydrate metabolism have been observed. 1. In the intact, suprareno-demedullated, and suprarenalectomized rat there is a progressive rise in the whole blood and plasma amino acid nitrogen levels during and after a ...
متن کاملBiochemical Studies on Inositol
In a previous publication (1, Paper V of this series) the purification and properties of the inositol-cleaving enzyme were described. It was shown that a highly purified enzyme was obtained from rat kidneys which cleaved inositol to D-ghCUI’OniC acid. The purified enzyme was shown to possess SH groups and 1 gram atom of iron per mole of enzyme. Both the SH groups and the iron are necessary for ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1961
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)63288-6