Comparative Analysis of the Antioxidant and Antidiabetic Potential of Nelumbo nucifera Gaertn. and Nymphaea lotus L. var. pubescens (Willd.)

Background. Nelumbo nucifera Gaertn. and Nymphaea lotus L. var. pubescens (Willd.) are both aquatic rhizomatous perennial plants mostly found in the tropical region of Nepal, India, Bangladesh, China, Eastern Asia. famous for their different biological activities such as antidiabetic, antioxidant, hepatoprotective, antidiarrheal, anti-inflammatory properties. Objective. The present study majorly focused on determination vitro antioxidant antidiabetic properties pubescens. Methods. In α-glucosidase inhibition was performed using PNPG a substrate. Antioxidant property plant extract determined by DPPH free radical scavenging assay. aluminium trichloride method done estimation total flavonoid content. Likewise, Folin–Ciocalteu reagent used determining phenolic Results. content N. to be 172.827 ± 0.41 194.87 0.93 mg GAE/g, respectively, while reported 17.12 1.04 34.59 1.73 QE/g, respectively. IC50 values crude its fractions against ranged from 33.46 0.6 3.52 0.09 μg/mL, that 14.30 0.43 1.43 0.08 μg/mL. Similarly, activity, varied 349.86 2.91 29.06 0.24 μg/mL 224.4 6.85 5.29 0.39 Conclusion. Both show can inhibit vitro. Further research is required identify inhibiting compounds.