Comparative analysis of CDR 3 regions in paired human αβ CD 8 T cells

Vitro Generated to Ex Vivo CD 8 T Cells Comparative and Functional Evaluation of In Juan

αβ T cell receptor germline CDR regions moderate contact with MHC ligands and regulate peptide cross-reactivity

αβ T cells respond to peptide epitopes presented by major histocompatibility complex (MHC) molecules. The role of T cell receptor (TCR) germline complementarity determining regions (CDR1 and 2) in MHC restriction is not well understood. Here, we examine T cell development, MHC restriction and antigen recognition where germline CDR loop structure has been modified by multiple glycine/alanine sub...

B Cells Directly Tolerize CD 8 1 T Cells

From the * Immunology Division, The Walter and Eliza Hall Institute of Medical Research, The Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia; ‡ The Cooperative Research Centre for Vaccine Technology at the Queensland Institute of Medical Research, The Royal Brisbane Hospital, Herston, Queensland 4029, Australia; and the § Department of Pathology and Immunology, Monash Medical Scho...

comparative analysis of the use of hedges & emphatics in english and persian academic research articles of sociology & psychology

چکیده ندارد.

Rapid Effector Function in CD 8 1 Memory T Cells

The nature of the CD8 1 T cells that underlie antiviral protective immunological memory in vivo is unclear. We have characterized peptide-specific CD8 1 T lymphocytes directly ex vivo from peripheral blood in humans with past exposure to influenza virus, using single cell interferon g (IFNg ) release as a measure of effector function. In individuals in the memory state with respect to influenza...