COMPACTION AND SPRINGBACK BEHAVIOUR OF SPRAY DRIED GRANULATES
نویسندگان
چکیده
منابع مشابه
Spray-Dried Lactose
pray-dried (SD) lactose was introduced to the pharmaceutical market in the 1960s as an excipient that enables direct compression of formulations in a simple manufacturing process (1). To this day, lactose remains one of the most popular excipients for active pharmaceutical ingredients (APIs) whose dose makes them suitable for direct compression. Several manufacturers make and sell SD lactose, a...
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We quantitatively studied the advantages of improving the compaction of a powder waste by several techniques, including its pelletization. The goal is increasing the mass storage capacity in a given storage volume, and reducing the permeability of air and moisture, that may trigger exothermic spontaneous reactions in organic waste, particularly as powders. The study is based on dried sludges fr...
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In this work, oven-dried, freeze-dried and spray-dried agaro-oligosaccharide powders were characterized to investigate their physicochemical and antioxidant properties. Agarooligosaccharide powders were shown to exhibit high water solubility index (88.73 – 95.88%), water absorption capacity (0.96 – 2.57 g/g) and oil absorption capacity (0.40 – 0.45 g/g). Agarooligosaccharide powders were shown ...
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Spray drying is a promising method for the stabilization of vaccines, which are usually formulated as liquids. Usually, vaccine stability is improved by spray drying in the presence of a range of excipients. Unlike freeze drying, there is no freezing step involved, thus the damage related to this step is avoided. The edge of spray drying resides in its ability for particles to be engineered to ...
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The bioavailability of hydrophobic drugs strongly increases if they are formulated as amorphous materials because the solubility of the amorphous phase is much higher than that of the crystal. Moreover, the stability of these particles against crystallization during storage increases with decreasing particle size. Hence, it is advantageous to formulate poorly water soluble drugs as amorphous na...
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ژورنال
عنوان ژورنال: Le Journal de Physique Colloques
سال: 1986
ISSN: 0449-1947
DOI: 10.1051/jphyscol:1986114