Community-acquired pneumonia guidelines: much guidance, but not much evidence

Community-acquired pneumonia guidelines: much guidance, but not much evidence.

Community-acquired pneumonia (CAP) is changing. The emergence and spread of antibiotic resistance in common causative bacteria, the development of new microbiological diagnostic techniques, new understandings in the area of severity assessment and the development of new antibiotics are just some of the issues. Methods of guideline writing have also evolved [1]. The categorisation of evidence an...

Community-acquired pneumonia guidelines: a global perspective.

Community-acquired pneumonia (CAP) is a common cause of morbidity and mortality worldwide, and since 1993, guidelines for management have been available. The process, which first began in the United States and Canada, has now been implemented in numerous countries throughout the world, and often each geographic region or country develops locally specific recommendations. It is interesting to re...

Much has changed, but much remains the same.

Photochemistry: let there be light--but not too much.

I t is hoped that artificial photosynthetic systems will one day be able to harness some of the energy in sunlight for applications such as solar energy, optoelectronics and molecular machines. For this to happen, however, these systems must be able to harvest the light, separate the electrons and ‘holes’ formed when the light is absorbed, and then transport these charges to places where they a...

Complete, accurate, mammalian phylogenies aid conservation planning, but not much.

In the face of unprecedented global biodiversity loss, conservation planning must balance between refining and deepening knowledge versus acting on current information to preserve species and communities. Phylogenetic diversity (PD), a biodiversity measure that takes into account the evolutionary relationships between species, is arguably a more meaningful measure of biodiversity than species d...