Common inflammatory mediators orchestrate pathophysiological processes in rheumatoid arthritis and atherosclerosis
نویسندگان
چکیده
منابع مشابه
Common inflammatory mediators orchestrate pathophysiological processes in rheumatoid arthritis and atherosclerosis.
RA is characterized by a systemic inflammatory state, in which immune cells and soluble mediators play a crucial role. These inflammatory processes resemble those in other chronic inflammatory diseases, such as atherosclerosis. The chronic systemic inflammation in RA can be considered as an independent risk factor for the development of atherosclerosis, and represents an important field to inve...
متن کاملInflammatory mediators in atherosclerosis.
54. Carew, T. E., Schwenke, D. C. & Steinberg, D. ( 1 987) /’roc. Natl. Acad. Sci. U.S.A. 84,7725-7729 Quinn, M. T., Parthasarathy, S., Fong, L. G. & Steinberg, D. (1987) Proc. Natl. Acad. Sci. U.S.A. 84,2995-2998 Steinberg, D., Parthasarathy, S., Carew, T. E., Khoo, J. C . & Witztum, J. L. ( 1989) N . Engl. J. Med. 320,9 15-924 Gey, K. F., Puska, P., Jordan, P. & Moser, U. K. ( 1 990) Am. J. C...
متن کامل[Rheumatoid arthritis and atherosclerosis].
Evidence continue to accumulate indicating that patients with rheumatoid arthritis (RA) present an increased risk of cardiovascular disease (and death). The risk factors for coronary artery disease (CAD) in RA are not fully understood. However, a number of possible factors have been described, but more than one may be efficient, such as homocysteine, presence of antiphospholipid antibodies, alt...
متن کاملAtherosclerosis in Rheumatoid Arthritis
1Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IFIMAV, 39008 Santander, Spain 2Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, 98 Nagyerdei Street, Debrecen H-4032, Hungary 3Department of Rheumatology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands 4Research Unit...
متن کاملInflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications.
BACKGROUND The time course and relationship between circulating and local cytokine concentrations, pancreatic inflammation, and organ dysfunction in acute pancreatitis are largely unknown. PATIENTS AND METHODS In a prospective clinical study, we measured the proinflammatory cytokines interleukin (IL)-1 beta, IL-6 and IL-8, the anti-inflammatory cytokine IL-10, interleukin 1 beta receptor anta...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2008
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/ken395