Commentary: Can subtle refinements of popular concepts be put into practice?

Can telomerase be put in its place?

The Cajal body is an intriguing nuclear structure present in a great variety of plant, animal, and some fungal cells. Recent work on the ribonucleoprotein enzyme telomerase has indicated an unanticipated degree of intranuclear dynamics of both its RNA and protein subunits. In this issue, Jady et al. place the Cajal body on the intranuclear traffic route of telomerase RNA (Jady et al., 2004).

Minimal Intervention in Dentistry Put into Practice

The minimal intervention in dentistry (MID) is a response to traditional concepts of operative dentistry developed by Black, more than a century ago. The MID philosophy is based on the knowledge of caries disease process and adhesive dentistry. Its main goal is to maintain tooth in function for life. Some procedures/protocols that represent MID philosophy are caries risk assessment, early carie...

Strategic philanthropy: principles put into practice.

The SeniorGezond Recommender: Exploration Put into Practice

Recommender systems suggest objects to users navigating a web site. They observe the pages that a user visits and predict which other pages may be of interest. On the basis of these predictions recommenders select a number of pages that are suggested to the user. By far the most popular recommendation strategy is to select the pages of which the recommender believes they are the most interestin...

Adoption of evidence into practice: can change be sustainable?

Few studies have monitored change in professional practice over time to determine the sustainability of change. Research from other behavioural change literature shows that initial change is difficult to maintain, with reported relapse rates as high as 80%. Interventions most likely to succeed are based on a clear understanding of target behaviours and the environmental context. Facilitators an...