Commentary: Accepting what we don’t know will lead to progress

Commentary: Accepting what we don't know will lead to progress.

ized clinical trials. J Clin Epidemiol 2002;55:407–10. 24. Ioannidis JP. A generalized view of self-citation: direct, co-author, collaborative, and coercive induced self-citation. J Psychosom Res 2015;78:7–11. 25. Nieminen P, Rucker G, Miettunen J, Carpenter J, Schumacher M. Statistically significant papers in psychiatry were cited more often than others. J Clin Epidemiol 2007;60:939–46. 26. Et...

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

Do We Know What We Do not Know? A Response to Celine Bonnet

Superior Capsule Reconstruction: What Do We Know?

The management of irreparable rotator cuff tears remains challenging. Since its introduction by Mihata in 2012, superiorcapsule reconstruction (SCR) has grown in popularity at an astonishingly rapid rate. The aim of this article is to providea comprehensive review of the available literature, in order to highlight what has so far been published on SCR,covering all aspects including biomechanica...

The origin of life: what we know, what we can know and what we will never know

The origin of life (OOL) problem remains one of the more challenging scientific questions of all time. In this essay, we propose that following recent experimental and theoretical advances in systems chemistry, the underlying principle governing the emergence of life on the Earth can in its broadest sense be specified, and may be stated as follows: all stable (persistent) replicating systems wi...