Comment on: “Switching Reference Medicines to Biosimilars: A Systematic Literature Review of Clinical Outcomes”

Switching Reference Medicines to Biosimilars: A Systematic Literature Review of Clinical Outcomes

INTRODUCTION To evaluate the possibility that switching from reference biologic medicines to biosimilars could lead to altered clinical outcomes, including enhanced immunogenicity, compromised safety, or diminished efficacy for patients, a systematic literature review was conducted of all switching studies between related biologics (including biosimilars). METHODS A systematic search was cond...

Impacts of Herbal Medicines on Hot Flash: A Systematic Review

Background: the most common symptoms experienced by women are Hot flashes are around the time of menopause. Many women are interested in herbal medicines because of fear of side effect of Hormone therapy. Objective: In this study, we seek to assess the effectiveness of herbal medicine on the recurrence of hot flash in menopausal women. Methods: The database of MEDLINE, Scopus, and the Co...

The effects of periodontal treatment on pregnancy outcomes: A systematic review of clinical trial studies

Background and Aim: Most recent systematic studies have reported on the role of periodontal disease in adverse pregnancy outcomes, which has paved the way for interventional studies in recent years; However, due to the limited number of clinical trial studies, the results of these studies have not yet been collected in a systematic study; Therefore, the aim of present  study was to evaluate the...

Are Biosimilars Identical to the Reference Products?

Are Biosimilars Identical to the Reference Products?