Comet assay comparison of different Corbicula fluminea (Mollusca) tissues for the detection of genotoxicity
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چکیده
منابع مشابه
Comet assay comparison of different Corbicula fluminea (Mollusca) tissues for the detection of genotoxicity
The comet assay was used to study the sensitivity of the widely distributed freshwater bivalve mollusk Corbicula fluminea to the DNA-damaging alkylating-agent methylmethane sulfonate (MMS). This study was undertaken to ascertain if C. fluminea is a good bioindicator of pollutants in aquatic environments and identify which C. fluminea tissue is most effective and practical for genotoxicity studi...
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Although the Comet assay, a procedure for quantitating DNA damage in mammalian cells, is considered sensitive, it has never been ascertained that its sensitivity is higher than the sensitivity of other genotoxicity assays in mammalian cells. To determine whether the power of the Comet assay to detect a low level of genotoxic potential is superior to those of other genotoxicity assays in mammali...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2005
ISSN: 1415-4757
DOI: 10.1590/s1415-47572005000300023