Combining controls can improve power in two-stage association studies
نویسندگان
چکیده
منابع مشابه
Multiethnic Genetic Association Studies Improve Power for Locus Discovery
To date, genome-wide association studies have focused almost exclusively on populations of European ancestry. These studies continue with the advent of next-generation sequencing, designed to systematically catalog and test low-frequency variation for a role in disease. A complementary approach would be to focus further efforts on cohorts of multiple ethnicities. This leverages the idea that po...
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ژورنال
عنوان ژورنال: BMC Genetics
سال: 2018
ISSN: 1471-2156
DOI: 10.1186/s12863-018-0675-y