Combined Pulmonary Fibrosis and Emphysema in a welder

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Combined pulmonary fibrosis and emphysema.

Combined pulmonary fibrosis and emphysema (CPFE) is a distinct clinical entity characterized by the simultaneous coexistence of both upper lobe emphysema and lower lobe pulmonary fibrosis. Although it was first described in 1990, it has not received enough recognition. Due to its unique lung function and clinical profile, pulmonologists should be aware of its existence while evaluating patients...

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Combined Pulmonary Fibrosis and Emphysema (CPFE)

Emphysema is characterized by the permanent abnormal enlargement of airspaces distal to the terminal bronchioles, accompanied by destruction of their walls. The characteristics of emphysema do not, by definition, include thickening of the alveolar septa and fibrosis. However, coincidental idiopathic pulmonary fibrosis (IPF) and emphysema was firstly reported in 1990 by Wiggins et al (Wiggins J,...

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Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity.

The syndrome resulting from combined pulmonary fibrosis and emphysema has not been comprehensively described. The current authors conducted a retrospective study of 61 patients with both emphysema of the upper zones and diffuse parenchymal lung disease with fibrosis of the lower zones of the lungs on chest computed tomography. Patients (all smokers) included 60 males and one female, with a mean...

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Combined Pulmonary Fibrosis and Emphysema, a clinical review

Combined Pulmonary Fibrosis and Emphysema (CPFE) refers to the coexistence of upper lobe predominant emphysema with diffuse pulmonary fibrosis, mainly in the lower lobes. Although initially described in patients with Idiopathic Pulmonary Fibrosis (IPF), since then it has been described in other forms of pulmonary fibrosis, most notably collagen tissue disorder associated interstitial lung disea...

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Combined pulmonary fibrosis and emphysema: a high-pressure situation.

T he combination of pulmonary fibrosis and emphysema (CPFE) was first described in 1990 by WIGGINS et al. [1]. Subsequent case studies further described what are now recognised as hallmarks of the syndrome: significant dyspnoea, a predilection for the disease among male smokers, normal or near normal lung volumes resulting from the opposing effects of hyperinflation and fibrosis, and a signific...

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ژورنال

عنوان ژورنال: Monaldi Archives for Chest Disease

سال: 2015

ISSN: 1122-0643

DOI: 10.4081/monaldi.2012.164