Combined interventional method of air-plasma flow and exogenous nitric oxide for the debridement of intracardiac infectious sites

Prosthetic valve endocarditis is a clinically severe pathology, which, unless timely treated, rapidly leads to the development of heart failure. The severity disease caused by fact that microorganisms and toxins bypass biological barriers constantly enter bloodstream, which subsequently results in sepsis with systemic embolism multiple organ conservative antibiotic therapy often ineffective due location infectious focus avascular zone. operations for prosthetic are technically challenging require high qualifications operating surgeon. article presents clinical case surgical treatment aortic valve. combined air-plasma flow exogenous nitric oxide (NO) using Plazon device without any antiseptic solutions was used as method debridement site.