Combined Expression of Transcription Factors Induces AR42J-B13 Cells to Differentiate into Insulin-Producing Cells
نویسندگان
چکیده
منابع مشابه
Changes in the expression of transcription factors in pancreatic AR42J cells during differentiation into insulin-producing cells.
Pancreatic AR42J cells possess both exocrine and neuroendocrine properties and convert to insulin-producing cells upon treatment with activin A and hepatocyte growth factor (HGF). We studied changes in the mRNA expression of various transcription factors during the course of differentiation. Among the transcription factors studied, expression levels of Pax4 and neurogenin3 changed significantly...
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ژورنال
عنوان ژورنال: Endocrine Journal
سال: 2008
ISSN: 0918-8959,1348-4540
DOI: 10.1507/endocrj.k07e-169