منابع مشابه
Combination therapy in combating cancer
Combination therapy, a treatment modality that combines two or more therapeutic agents, is a cornerstone of cancer therapy. The amalgamation of anti-cancer drugs enhances efficacy compared to the mono-therapy approach because it targets key pathways in a characteristically synergistic or an additive manner. This approach potentially reduces drug resistance, while simultaneously providing therap...
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Addis Tesfa With funding from the Centers for Disease Control and Prevention (CDC), the Addis Tesfa (New Hope) Project is a collaboration between Pathfinder International, the Ethiopian Federal Ministry of Health (FMOH), and the Stanford University Program for International Reproductive Education and Services (SPIRES). The Project’s goal is to develop a model for integrating the single-visit ap...
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Three-drug therapy with Mitomycin-C (MMC), 5-fluorouracil (5-FU), and a nitrosourea derivative, ACNU, was carried out in 72 cases of carcinoma patients, mostly of stomach carcinoma. 1) According to Karnofsky's criteria, an effect of above I-A was observed in 10 of 35 cases (29%) treated with MFU-I (0.08 mg/kg of MMC, 10 mg/kg of 5-FU and 0.4-0.8 mg/kg of ACNU twice a week for the first two week...
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Rat experimental models are used extensively for studying physiological mechanisms and treatments of hypertension and diabetes co-existence. Each one of these conditions is a major risk factor for cardiovascular disease (CVD), and the combination of the two conditions is a potent enhancer of CVD. Five major animal models that advanced our understanding of the mechanisms and therapeutic approach...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.16723