Combination chemotherapy in recurrent medulloblastoma
نویسندگان
چکیده
منابع مشابه
High-dose chemotherapy for recurrent medulloblastoma: time for a reappraisal.
M ore than a decade ago, Finlay et al. published a landmark article in which they demonstrated that a subset of patients with recurrent brain tumors of diverse histologic diagnosis could be salvaged with high-dose chemotherapy followed by autologous stem cell rescue. The preparatory regimen included only 2 drugs: thiotepa and etoposide. Hematopoietic growth factors were used to enhance count re...
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Tumours of the central nervous system (CNS) are the second most common childhood malignant diseases after hematological malignancies. The incidence is similar in the different developed countries: in Europe is 29.9/million (1978-1997), in USA 30.7/million (1992-2006). However, the highest incidence is registered in Hungary and the Scandinavian countries. In Hungary the incidence was 37.41/milli...
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BACKGROUND We assessed the efficacy and toxicity of ifosfamide and doxorubicin combination chemotherapy (CT) regimen retrospectively in Turkish patients with recurrent or metastatic nasopharyngeal carcinoma (NPC) previously treated with platinum-based chemotherapy. METHODS A total of thirty patients who had received cisplatin based chemotherapy/chemoradiotherapy as a primary treatment receive...
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The human glioma-derived cell line D-54 MG and the human medulloblastoma-derived cell line TE-671 have been shown to be sensitive in culture to the pharmacological interference with glutamine metabolism by acivicin, 6-diazo-5-oxo-L-norleucine, and methionine sulfoximine. Using as a guide the multiple contributions of glutamine to the biosynthesis of proteins, purines, and pyrimidines, we now ha...
متن کاملPre-irradiation chemotherapy in high risk medulloblastoma.
RATIONALE The present study evaluates the effect of pre-irradiation chemotherapy in pediatric patients with high risk medulloblastoma. Twenty-four (24) pediatric patients attended the pediatric unit of Kasr-El-Aini Center of Radiation Oncology and Nuclear Medicine (NEMROCK) from January 2000 to January 2003. PATIENTS AND METHODS Our patients were 13 boys and 11 girls aged 3-12 years with a me...
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ژورنال
عنوان ژورنال: Cancer
سال: 1979
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197901)43:1<41::aid-cncr2820430105>3.0.co;2-u