منابع مشابه
Advances in understanding hypopituitarism
The understanding of hypopituitarism has increased over the last three years. This review provides an overview of the most important recent findings. Most of the recent research in hypopituitarism has focused on genetics. New diagnostic techniques like next-generation sequencing have led to the description of different genetic mutations causative for congenital dysfunction of the pituitary glan...
متن کاملHypopituitarism in childhood.
BACKGROUND Childhood hypopituitarism may be present at birth or may be acquired. Early diagnosis and treatment promote the best possible outcomes. METHODS The anatomy, etiologies, clinical presentation, diagnostic testing strategies, and current treatments relevant to childhood hypopituitarism are reviewed. RESULTS Children with congenital hypopituitarism may present with life-threatening h...
متن کاملHypopituitarism in first cousins.
There is still much difficulty in elucidating the aetiological causes of dwarfism as it presents itself in children. After Erdheim in 1916 attributed dwarfism to a lack of pituitary secretion, it was for many years a common habit to implicate a pituitary deficiency in alJ dwarfs whatever their clinical features. A reaction to this unscientific approach was to be expected, and it has been so ext...
متن کاملMortality in Hypopituitarism Causes Clinical Features Diagnosis and Endocrine Assessment Treatment of Hypopituitarism Strategies to Prevent Hypopituitarism
Hypopituitarism is the deficiency of one or more pituitary hormones. It is relatively rare, with a prevalence of 45 per million and an annual incidence of about 4 per 100,000.1 It is, however, seen commonly in endocrine practice and, importantly, is associated with increased morbidity and mortality. Clinical manifestations are influenced by the etiology, severity, and rate of onset of pituitary...
متن کاملDiagnosis of hypopituitarism in childhood.
The diagnosis of hypopituitarism in childhood, particularly in the idiopathic type, has been a matter of great difficulty. Growth retardation is the constant presenting sign, and since this is a common occurrence in childhood, differential diagnosis has required an assessment of the clinical story and the results of investigations which too often have not yielded a precise answer. Most of the c...
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ژورنال
عنوان ژورنال: BMJ
سال: 1955
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.4946.1022