Collagenase Clostridium histolyticum:emerging practice patterns and treatment advances
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چکیده
منابع مشابه
Collagenase Clostridium histolyticum : emerging practice patterns and treatment advances
OBJECTIVE This study aims to provide a comprehensive review of the role of Collagenase Clostridium histolyticum (CCH). METHODS This review is based on a literature review and practical experience. RESULTS This review provides practical management strategies for using collagenase by sharing clinical experiences over the past few years; logistical aspects of in-clinic treatment, lessons learn...
متن کامل[Treatment of Dupuytren's disease using collagenase from Clostridium histolyticum].
OBJECTIVE The collagenase from Clostridium histolyticum is a new therapeutic option, and the first pharmacological one, in the treatment of Dupuytren's disease. MATERIAL AND METHODS A prospective study was conducted on 35 patients with Dupuytren's disease. The clinical and functional variables, as well as patient satisfaction and drug safety were evaluated. RESULTS The functional and clinic...
متن کاملCollagenase clostridium histolyticum: a novel nonoperative treatment for Dupuytren’s disease
Dupuytren’s disease is a progressive disease of the palmar and digital fascial structures of the hand characterized by abnormal collagen deposition, nodular thickening of the palmar aponeurosis and subsequent joint contracture. Contracture occurs primarily at the metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joint levels (Figure 1). Although pathologically benign, Dupuytren’s con...
متن کاملInjectable collagenase clostridium histolyticum for Dupuytren's contracture.
BACKGROUND Dupuytren's disease limits hand function, diminishes the quality of life, and may ultimately disable the hand. Surgery followed by hand therapy is standard treatment, but it is associated with serious potential complications. Injection of collagenase clostridium histolyticum, an office-based, nonsurgical option, may reduce joint contractures caused by Dupuytren's disease. METHODS W...
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ژورنال
عنوان ژورنال: Journal of Plastic Surgery and Hand Surgery
سال: 2016
ISSN: 2000-656X,2000-6764
DOI: 10.3109/2000656x.2016.1159568