Collagen binding site in collagenase can be determined using the concept of sense-antisense peptide interactions.
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چکیده
منابع مشابه
Collagen binding site in collagenase can be determined using the concept of sense-antisense peptide interactions.
Tissue degradation and invasion are hallmarks of the metastatic phenotype. While several extracellular matrix components can be digested by proteases, degradation of interstitial collagen is selectively initiated by collagenase. It is obvious that inhibitors of collagenase activity would be extremely useful in preventing tissue destruction and tumor cell invasion and thus prove invaluable thera...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)42279-x