Colibri® insecticide induces male reproductive toxicity: alleviating effects of Lannea acida (Anacardiaceae) in rats

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long-term administration of artesunate induces reproductive toxicity in male rats

background: artesunate is commonly used in malaria therapy. many antimalarial drugs have been associated with male reproductive dysfunction. the effect of artesunate on male reproductive activities was studied using in–vivo and in-vitro experimental models. methods: adult male rats (n=6) were orally given artesunate (2.9 mg/kg body weight) on daily basis for five days. artesunate (2.9 mg/kg bod...

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the effect of aqueous extract of garlic on formalin-induced pain in male rats

چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...

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Long-Term Administration of Artesunate Induces Reproductive Toxicity in Male Rats

BACKGROUND Artesunate is commonly used in malaria therapy. Many antimalarial drugs have been associated with male reproductive dysfunction. The effect of artesunate on male reproductive activities was studied using in-vivo and in-vitro experimental models. METHODS Adult male rats (n=6) were orally given artesunate (2.9 mg/kg body weight) on daily basis for five days. Artesunate (2.9 mg/kg bod...

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Perinatal exposure to insecticide fipronil: effects on the reproductive system in male rats.

Fipronil is an insecticide widely used in agriculture, veterinary medicine and public health that has recently been listed as a potential endocrine disrupter. In the present study we evaluated the effects of perinatal exposure to fipronil during the period of sexual brain differentiation and its later repercussions on reproductive parameters in male rats. Pregnant rats were exposed (via gavage)...

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Effects of pyrethroid insecticide ICON (lambda cyhalothrin) on reproductive competence of male rats.

AIM To assess the effect of ICON (trade name of lambda-cyhalothrin) on sexual competence and fertility of male rats. METHODS Male rats were gavaged daily for 7 consecutive days with different doses of ICON (63 mg/kg and 100 mg/kg) or vehicle (distilled water). Their sexual behaviour and fertility were evaluated at different time points during treatment and post-treatment using receptive femal...

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ژورنال

عنوان ژورنال: Basic and Clinical Andrology

سال: 2019

ISSN: 2051-4190

DOI: 10.1186/s12610-019-0096-4