Cold agglutinins revelated by abnormalities to the cell blood count

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Chronic hemolytic anemia due to cold agglutinins: the mechanism of resistance of red cells to C' hemolysis by cold agglutinins.

The red cells of patients with chronic hemolytic anemia due to cold agglutinins are agglutinated by antiglobulin serum in a nongamma reaction due to the coating of beta-globulins, C'4 and C'3. The red cells of such patients are abnormally resistant to C' hemolysis by cold agglutinin. Normal red cells can be made equally resistant to C' hemolysis by incubation with cold agglutinin and normal ser...

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Platelet cold agglutinins.

A “cold” platelet agglutinin is described reacts only at temperatures below 34#{176}C. which is present in plasma and serum, It agglutinates homologous and autois greater than 100,000 in molecular logous platelets but appears to have no weight, appears to be a protein of the imeffect on in vivo platelet function. It is munoglobulin type, is adsorbed by plateseen in patients with systemic diseas...

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How I manage cold agglutinins.

From the Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan. Address reprint requests to: W. John Judd, FIBMS, MIBiol, Professor of Immunohematology, Department of Pathology, UH-2G332, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0054; e-mail: [email protected]. Received for publication November 2, 2005; accepted No...

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Cold agglutinins in the West African soldier.

I am grateful to Major-General J. Huston, Q.H.S., F.R.C.S., Director of Surgery, for his advice and encouragement and to Captain G. Tate, R.A.M.C., and Mr. A. E. Pridham, for their help. REFERENCES FINNEY, J. M. J., & HANRAHAN, E. M. (1930). Ann. Surg., 92, 620. GOLlGHER, J. C., MOIR, P. J. & WRIGLEY, J. H. (1956). Lancet, 1, 220. McDoNALD, O. G., GILLESPIE, M. G. & LA BREE, R. H. (1953). A.M.A...

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Effect of Thyroid Dysfunctions on Blood Cell Count and Red Blood Cell Indice

Abstract Background Thyroid hormones have a crucial role in metabolism and proliferation of blood cells. Thyroid dysfunction induces different effects on blood cells such as anemia, erythrocytosis leukopenia, thrombocytopenia, and in rare cases causes’ pancytopenia. It also alter RBC indices include MCV, MCH, MCHC and RDW. Thus this study attempted to evaluate effect of hypo & hyperthyroi...

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ژورنال

عنوان ژورنال: Pan African Medical Journal

سال: 2021

ISSN: 1937-8688

DOI: 10.11604/pamj.2021.38.328.9100