Cognitive Impairment in Studies of 5HTTLPR and Psychosis in Alzheimer’s Disease: A Systematic Review

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Cognitive impairment in studies of 5HTTLPR and psychosis in Alzheimer's disease: a systematic review.

BACKGROUND/AIMS Cognitive impairment is a well-established correlate of psychotic symptoms in Alzheimer's disease (AD-P). We review whether this relationship has confounded previous genetic association studies of 5HTTLPR and AD-P. METHODS We reviewed all studies on 5HTTLPR and conducted a semi-quantitative analysis. RESULTS Three out of 4 studies with low MMSE reported a significant associa...

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ژورنال

عنوان ژورنال: Dementia and Geriatric Cognitive Disorders

سال: 2013

ISSN: 1421-9824,1420-8008

DOI: 10.1159/000346733