Cognitive deficits at age 22 years associated with prenatal exposure to methylmercury
نویسندگان
چکیده
منابع مشابه
Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years.
A cohort of 1022 consecutive singleton births was generated during 1987-1988 in the Faroe Islands, where increased methylmercury exposure occurs from traditional seafood diets that include pilot whale meat. The prenatal exposure level was determined from mercury analyses of cord blood, cord tissue, and maternal hair. At age 14 years, 878 of 1010 living cohort members underwent detailed neurobeh...
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BACKGROUND Prenatal alcohol exposure (PAE) affects central nervous system development, growth, and morphology at higher exposure levels. Little is known about the effects of PAE at lower exposure levels or in young adults. Research on children with higher levels of PAE has shown that PAE predicts behavior problems. The question remains whether these effects are permanent or ameliorated by matur...
متن کاملCognitive deficits and changes in gene expression of NMDA receptors after prenatal methylmercury exposure.
Previous studies showed learning and memory deficit in adult rats that were prenatally exposed to methylmercury chloride (MMC) in an advanced stage of pregnancy (15 days). Under these conditions, the cognitive deficits found at 60 days of age paralleled particularly changes in the N-methyl-D-aspartate (NMDA) receptor characteristics. In the present study, we report the behavioral effects of a s...
متن کاملPrenatal famine exposure and cognition at age 59 years.
BACKGROUND Despite the perceived importance of early life nutrition for mental development, few studies have related gestational undernutrition to later-life cognitive functioning. We investigated the consequences of gestational exposure to the Dutch famine of 1944-45 for cognitive functioning at the age of 59 years. METHODS We recruited men and women who were (i) born in birth clinics in Ams...
متن کاملMaternal PUFA status but not prenatal methylmercury exposure is associated with children's language functions at age five years in the Seychelles.
Evidence from the Seychelles Child Development Nutrition Study suggests that maternal nutritional status can modulate the relationship between prenatal methylmercury (MeHg) exposure and developmental outcomes in children. The aim of this study was to investigate whether maternal PUFA status was a confounding factor in any possible associations between prenatal MeHg exposure and developmental ou...
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ژورنال
عنوان ژورنال: Cortex
سال: 2016
ISSN: 0010-9452
DOI: 10.1016/j.cortex.2015.05.017