Coenzyme Q

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Coenzyme Q 10 : a Review

Ubiquinone or Co Q(10) is essentially a vitamin like substance and is a cofactor of an enzyme. It is an integral part of the memberanes of mitocondria where it is involved in the energy production. It is a nutrient necessary for the function of every cell of the body especially vital organs of the body like heart, liver, brain etc. Studies have shown that coenzyme Q(10) alters the natural histo...

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Coenzyme Q and mitochondrial disease.

Coenzyme Q(10) (CoQ(10)) is an essential electron carrier in the mitochondrial respiratory chain and an important antioxidant. Deficiency of CoQ(10) is a clinically and molecularly heterogeneous syndrome, which, to date, has been found to be autosomal recessive in inheritance and generally responsive to CoQ(10) supplementation. CoQ(10) deficiency has been associated with five major clinical phe...

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Coenzyme q and the respiratory chain: coenzyme q pool and mitochondrial supercomplexes.

Two alternative models of organization of the mitochondrial electron transport chain (mETC) have been alternatively favored or questioned by the accumulation evidences of different sources, the solid model or the random collision model. Both agree in the number of respiratory complexes (I-IV) that participate in the mETC, but while the random collision model proposes that Complexes I-IV do not ...

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Endogenous synthesis of coenzyme Q in eukaryotes.

Coenzyme Q (Q) functions in the mitochondrial respiratory chain and serves as a lipophilic antioxidant. There is increasing interest in the use of Q as a nutritional supplement. Although, the physiological significance of Q is extensively investigated in eukaryotes, ranging from yeast to human, the eukaryotic Q biosynthesis pathway is best characterized in the budding yeast Saccharomyces cerevi...

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Possible Health Benefits of Coenzyme Q 10

Ubiquinone, or coenzyme Q (CoQ), was discovered in 1957 by Fred Crane. Its chemical structure was determined a few years later by Karl Folkers, who later won the Priestley medal from the American Chemical Society. CoQ plays an important role in the production of chemical energy in the mitochondria. In its reduced form, ubiquinol, CoQ also serves as an antioxidant. Ubiquinol inhibits lipid perox...

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ژورنال

عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan

سال: 1969

ISSN: 0037-9980,1883-6526

DOI: 10.5059/yukigoseikyokaishi.27.138