Codon optimization enhances the expression of porcine β-defensin-2 in Escherichia coli
نویسندگان
چکیده
منابع مشابه
Codon optimization enhances the expression of porcine β-defensin-2 in Escherichia coli.
Porcine β-defensin-2 (pBD2) is a cationic antimicrobial peptide that has therapeutic potential. The amount of pBD2 in nature is limited, and the expression of pBD2 in Escherichia coli is low, probably because a different gene codon is used by prokaryotic organisms to that used by eukaryotes. Codon preference optimization is one of the ways to increase heterologous expression of pBD2. To achieve...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2015
ISSN: 1676-5680
DOI: 10.4238/2015.may.12.1