Codelivery of thioridazine and doxorubicin using nanoparticles for effective breast cancer therapy

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Codelivery of thioridazine and doxorubicin using nanoparticles for effective breast cancer therapy

Cancer chemotherapy can benefit from the combination of different anticancer drugs. Here, we prepared doxorubicin (Dox)- and thioridazine (Thio)-coloaded methoxy poly(ethylene glycol)-poly(l-lactic acid) (MPEG-PLA) nanoparticles (NPs) for breast cancer therapy. These NPs have an average particle size of 27 nm. The drug loading efficiencies of Thio and Dox are 4.71% and 1.98%, respectively. Comp...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2016

ISSN: 1178-2013

DOI: 10.2147/ijn.s104635