Cocaine, Benzoylecgonine Amphetamine, and N-Acetylamphetamine Bincling to Melanin Subtypes
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چکیده
منابع مشابه
Addiction to Cocaine and Amphetamine
but not DA reuptake, produce neither significant reinforcement in animal models nor euphoria in humans. Laboratory of Molecular and Developmental Neuroscience Moreover, antidepressants do not produce dependence in humans even with very long-term use. In addition, Massachusetts General Hospital Harvard Medical School lesioning of DA terminals within the NAc or full pharmacological blockade of DA...
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A high-throughput Liquid chromatography/ Mass spectrometry/ Mass spectrometry (LC/MS/MS) method for simultaneous quantification of cocaine (COC) and benzoylecgonine (BZE) in human plasma was elaborated. After the protein precipitation with methanol in the plasma samples, the analytes were separated on a Zorbax SB-C18 column under isocratic conditions using a 32:68 (v/v) mixture of methanol and ...
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Certain antidepressant and psychostimulant drugs block the uptake of norepinephrine from the synaptic cleft by inhibiting norepinephrine transporter (NET) function. The effects of chronic occupation of the NET by these drugs on NET expression are poorly understood. We previously described down-regulation of the NET in cultured cells after continuous exposure to the tricyclic antidepressant desi...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2003
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/27.3.125