منابع مشابه
CMR myocardial tissue characterization in a mouse model of doxorubicin-induced cardiotoxicity
Background Cardiotoxicity is a major limiting factor preventing dose-effective use of multiple cytotoxic agents in cancer treatment. Current cardiotoxicity diagnosis is based on functional changes that occur late in the course of the disease. In this pre-clinical pilot study, we hypothesize myocardial T1 and T2 mapping will identify mice at risk of death secondary to doxorubicin-induced cardiot...
متن کاملQuantitative tissue characterization of cardiac myxomas by CMR-Mapping techniques validated by histology
Methods 10 patients with morphologically suspected cardiac myxomas on echocardiography and confirmed by post-operative histopathology were prospectively included. CMR was performed at 1.5 Tesla in all patients pre-operatively. Standard protocol for cardiac mass assessment included T1 mapping (pre and post contrast to calculate ECV) and T2 mapping. All data are reported as mean ± standard deviat...
متن کاملCMR-based characterization of cardiac amyloidosis.
Amyloidosis is a systemic disease caused by the deposition of misfolded proteins. Cardiac involvement is a major cause of morbidity and mortality, especially in the light chain (AL) and transthyretin (ATTR) forms. Amyloidosis usually presents as a restrictive cardiomyopathy with progressive systolic/ diastolic dysfunction and arrhythmias but is often misdiagnosed as hypertrophic or hypertensive...
متن کاملReply: CMR-Based Characterization of Cardiac Amyloidosis.
We thank Barison et al. for their interest in our paper (1). Cardiac amyloidosis is gaining significant exposure in the cardiac magnetic resonance (CMR) community because of the characteristic and near pathognomonic findings with the technique. We reported the first study that specifically aimed to differentiate between the light chain (AL) and transthyretin (ATTR) subtypes of amyloidosis throu...
متن کاملsynthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2019
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2019.03.521