CLRM-08 TAILORING CLINICAL TRIALS TO INCREASE PATIENT ENGAGEMENT: IMPACT ON PATIENT-REPORTED OUTCOMES IN ONCOLOGY

Abstract BACKGROUND As regulators put more attention on patient-reported outcomes (PROs) in oncology clinical trials, it is vital to understand patient preferences and motivation for completing PROs. We investigated motivations symptom reporting how this may differ between participants with cancer other chronic non-oncology diseases. METHODS Participants completed an online survey focusing using devices report symptoms what motivates them complete Statistical analyses included a descriptive analysis of responses Chi-Squared tests examine differences subgroups (oncology vs. arthritis, diabetes, obstructive pulmonary disease). RESULTS (N = 16) preferred their own smartphone (31%) over going website (19%) or study-dedicated device (6%) symptoms, 44% being happy any option (44%). 88% reported that receiving regular information help manage would motivate the most PROs basis. Receiving small financial compensation (81%) knowing data was reviewed by healthcare professional (75%) were also strong motivators The least motivator form charity donations (25%). Preference differed (p=0.04), such showed higher preference compared subgroup (N=30). likely notifications alarms (p=0.04) as strategies encourage CONCLUSION This exploratory suggests importance considering range potential tailoring fit preferences. use personal smartphones Bring-Your-Own-Device (BYOD) strategy be particularly suited trials.