منابع مشابه
Clotting and fibrinolysis.
Vascular disease accounts for more than 50% of deaths and in most cases the cause lies in obstruction to blood flow by the twin perils of atheroma formation and thrombosis. The major constituents of thrombi are platelets and fibrin, together with trapped red cells and other elements. Our main antithrombotic drugs are the antiplatelet agents to prevent platelets sticking together; anticoagulants...
متن کاملBlood clotting and fibrinolysis in pregnancy.
During normal pregnancy, the concentrations of many of the clotting factors rise, thereby increasing the potential to generate fibrin. There is also evidence of increased thrombin activity during normal pregnancy which sharply increases during placental separation. Antithrombin III, the main inhibitor of thrombin and activated factor X, shows no compensatory rise during pregnancy but increases ...
متن کاملBlood clotting and fibrinolysis in areas with different water supplies.
A sample of venous blood was taken from each subject. Some of this (5 ml) was mixed with fresh 3 * 8% sodium citrate, 9 : 1 volumes blood to citrate, spun immediately at 3,000 r.p.m. for 10 minutes in a MSE centrifuge and the plasma was separated and deep frozen immediately. Two millilitres of blood were mixed with 20J1 of Trasylol and allowed to clot overnight, and then the serum was separated...
متن کاملClotting activation and impairment of fibrinolysis in malignancy.
Different coagulation and fibrinolysis parameters were investigated in 149 patients with metastatic and non-metastatic tumours and results were compared with those obtained in a healthy population. Results showed a significant increase of thrombin-antithrombin complexes, fibrinopeptide A (FPA) and fibrin monomers in the group of patients (p less than 0.001). There was also a significant prolong...
متن کاملSaliva-Induced Clotting Captures Streptococci: Novel Roles for Coagulation and Fibrinolysis in Host Defense and Immune Evasion
Streptococcal pharyngitis is among the most common bacterial infections, but the molecular mechanisms involved remain poorly understood. Here we investigate the interactions among three major players in streptococcal pharyngitis: streptococci, plasma, and saliva. We find that saliva activates the plasma coagulation system through both the extrinsic and the intrinsic pathways, entrapping the bac...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1975
ISSN: 0021-9746
DOI: 10.1136/jcp.28.suppl_9.50