Cloning of the human cDNA for transcription factor pit-1

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Cloning of the human cDNA for transcription factor Pit-1.

The mammalian pit-1 gene encodes a 33 kd transcription factor (1,2) expressed in a subset of endocrine cells of the anterior pituitary (3). Pit-1 is structurally related to the POU family of transcriptional regulators (4), containing a characteristic POU domain divided into two regions, the POU-specific and homeo subdomains. Located in the C-terminal half of the protein, the POU domain is criti...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1991

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/19.22.6329