CLONIDINE TREATMENT IN CHILDREN WITH CONSTITUTIONAL GROWTH DELAY (CGO)

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Constitutional Delay Influences the Auxological Response to Growth Hormone Treatment in Children with Short Stature and Growth Hormone Sufficiency

In a retrospective, population based cohort study, we examined whether constitutional delay was associated with the growth response to growth hormone (GH) in children with short stature and normal GH responses. 70 patients were treated with 21 GH iu/m2/week from 1975 to 2013 throughout New Zealand. Demographic and auxological data were prospectively collected and standard deviation scores (SDS)...

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Treatment of constitutional delay of growth and puberty with oxandrolone compared with growth hormone.

The effects of oxandrolone or biosynthetic human growth hormone (r-hGH) on the growth of 26 boys with constitutional delay of growth and puberty were studied. Both regimens increased growth rate twofold, oxandrolone to a greater extent than r-hGH. We conclude that oxandrolone is a more effective method of increasing growth rate in such children.

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Ghrelin Levels in Children with Constitutional Delay of Growth and Puberty

OBJECTIVE In this study, we aimed to show the role of ghrelin in growth delay in children with constitutional delay of growth and puberty (CDGP). METHODS Thirty male children with CDGP constituted the study group and fifteen healthy children with normal growth of similar ages-the control group. In both groups, fasting and postprandial plasma ghrelin levels, serum insulin-like growth factor-1 ...

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Bone mineral status in prepubertal children with constitutional delay of growth and puberty.

OBJECTIVE We wished to clarify whether the osteopenia reported in adult men with a history of constitutional delay of growth and puberty (CDGP) could be due to the delayed puberty or an independent predisposition to osteoporosis in this condition. DESIGN Short prepubertal children with CDGP and children with familial short stature (FSS) were matched for height and other auxological variables....

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Treatment of constitutional growth delay in prepubertal boys with a prolonged course of low dose oxandrolone.

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1988

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-198801000-00144