Clonazepam

Pancytopenia associated with clonazepam

We report a case of a 48-year-old Chinese female with end-stage renal disease and chronic anemia on hemodialysis. Clonazepam was prescribed for myoclonus disorder two weeks prior to her hospitalization. Subsequently, she was hospitalized for neutropenic fever with thrombocytopenia and worsening anemia. Bone marrow examination demonstrated a markedly hypocellular marrow (10-20% total cellularity...

Is Topical Clonazepam More Effective Than Oral Clonazepam in Treatment of Burning Mouth Syndrome (BMS)?

A Case Report of Clonazepam Dependence

Clonazepam is long-acting benzodiazepine agonist used in short-acting benzodiazepine withdrawal; however, recent observations suggest the existence of its abuse. We demonstrate a 40-year-old man with a 20-year history of psychiatric care with recently benzodiazepine dependence (daily intake of 60 mg of clonazepam and 10 mg of alprazolam). High serum levels of both drugs were analyzed 3 weeks be...

Clonazepam suppresses oscillations in rat thalamic slices

Hypersynchrony of spindle-like thalamic oscillations may contribute to thalamic dysrhythmias including generalized absence epilepsy. Here we show that, as predicted by previous modeling studies, enhancement of inhibition between thalamic reticular (RE) cells by clonazepam suppresses evoked oscillations in rat thalamic slices. We also observed spontaneous oscillations, which have a variable and ...

Pulsatile tinnitus: treatment with clonazepam and propranolol.

Pulsatile tinnitus synchronous with heartbeat is rare and normally has vascular origin: arterial (malformation, arterial anatomical variation) or venous (aberrant jugular bulb, glomus tumors, tympanic glomus tumor). Early etiology identification is essential for appropriate treatment to be established. Magnetic angioresonance makes the vascular identification possible and precise. We report a c...