Clomiphene Citrate for Male Hypogonadism and Infertility: An Updated Review
نویسندگان
چکیده
منابع مشابه
Clomiphene citrate treatment for late onset hypogonadism: rise and fall
OBJECTIVE Previous series have demonstrated that Clomiphene Citrate (CC) is an effective treatment to increase Total Testosterone (TT) in Late Onset Hypogonadism (LOH) patients. However, what happens to TT levels after ending CC treatment is still debatable. The objective of this study is to evaluate TT levels 3 months after the discontinuation of CC in patients with LOH who were previously suc...
متن کاملSafety and efficacy of clomiphene citrate and L-carnitine in idiopathic male infertility: a comparative study.
PURPOSE To compare the effects of L-carnitine with clomiphene citrate in idiopathic infertile men. MATERIALS AND METHODS Fifty-two men with idiopathic infertility were recruited in this randomized controlled trial. They were randomly assigned into 2 treatment groups, group 1 (n = 20) and group 2 (n = 32), who received L-carnitine 25 mg/day and clomiphene citrate 2 gr/day, respectively, for a ...
متن کاملLetrozole versus Clomiphene Citrate in Patients with Anovulatory Infertility
Objective: To compare the effectiveness of letrozole and clomiphene citrate (CC) in patients with anovulatory infertility. Design: Open, prospective, randomized, parallel group, multicentric, comparative trial. Setting: Outpatient clinics of infertility centers in India. Patient(s): Fifty-five patients with anovulatory infertility were recruited. Twenty-seven patients (59 cycles) were given let...
متن کاملClomiphene for anovulatory infertility.
Evidence • Systematic review of RCTs of antiestrogens in PCOS1: -In 3 RCTs (N = 133) that examined clomiphene (50 to 250 mg/d, 1 to 5 cycles) versus placebo, the pregnancy rate was higher with clomiphene (20% vs 3%); the number needed to treat (NNT) was 6. Live births and miscarriages were not reported. -Limitations: small sample, variable dosing and number of cycles, high dropout rate, poor ad...
متن کاملClomiphene citrate--end of an era? A mini-review.
The purpose of this review is to examine whether the time has come to replace clomiphene citrate (CC) as the first line therapy for WHO group II (eu-oestrogenic) infertility, the majority of which is associated with polycystic ovary syndrome. CC has been the first line therapy for these cases for the last 40 years. It is a simple, cheap treatment, almost devoid of side effects which yields a si...
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ژورنال
عنوان ژورنال: Androgens: Clinical Research and Therapeutics
سال: 2020
ISSN: 2689-4653
DOI: 10.1089/andro.2020.0005