Clinicopathological changes associated with Campylobacter jejuni inecftion in broilers

The present study aimed to investigate the prevalence of Campylobacter (C) and its clinicopathological changes in broilers Sharkia province, About 50 diarrheic cloacal swabs were collected for bacteriological examination. Out exami-ned 12 (24%) positive [C. coli 4 C. jejuni 8]. Isolated was sensitive neomycin genta-ycin. 45 healthy one day-old received 5 mg pefloxacin/kg bwt days proved that free from bacterial infections. At 14th day age divided into 3 groups (15/ each). 1st group non treated (control), 2nd 3rd infected with jejuni. infected, 15 neomycin/kg B.wt. drinking water days. 1st, 7th and14th post treatment re-isolation beside blood samples hematochemical study. Infected showed food, depression, ruffled feather, diarrhea mortality rate 40% significant decrease body performance, total protein albumin, globulin coupled insignificant elevation RBCs, HB, PCV%, WBCs, AST, ALT, ALP, urea creatinine. Treatment broi-lers by lead disappear clinical sing, reduced improved hematobiochemical parameters. It could be concluded Campylobact-er infection induces reversible adverse effect on performance hematobioc- al Neomycin is highly curative against campylobacters