Clinical value of cough swab samples, versus induced sputum samples in children with cystic fibrosis

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Cough plate versus cough swab in patients with cystic fibrosis; a pilot study.

BACKGROUND Accurate identification of lower respiratory tract pathogens is important in the management of cystic fibrosis patients. AIM To evaluate the cough plate as an alternative method of obtaining respiratory samples for microbiological culture. METHODS AND RESULTS Using sputum culture as the "gold standard", the cough plate method identified significantly more positive cases than eith...

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Conformity of bacterial growth in sputum and contamination free endobronchial samples in patients with cystic fibrosis.

The use of sputum cultures to guide the antimicrobial treatment of patients with cystic fibrosis has been questioned. Bacterial growth and antibiotic susceptibility patterns of 33 culture pairs from sputum and contamination free endobronchial swabs from 14 patients with cystic fibrosis were compared. As expected, Pseudomonas aeruginosa of the mucoid and non-mucoid type, Staphylococcus aureus, a...

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Diagnosis of respiratory viral infections in cystic fibrosis by PCR using sputum samples.

REFERENCES 1 Jones AM, Govan JR, Doherty CJ, et al. Spread of a multiresistant strain of Pseudomonas aeruginosa in an adult cystic fibrosis clinic. Lancet 2001; 358: 557–558. 2 Cheng K, Smyth RL, Govan JR, et al. Spread of b-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis clinic. Lancet 1996; 348: 639–642. 3 Armstrong DS, Nixon GM, Carzino R, et al. Detection of a widespread clone ...

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High-level beta-lactamase activity in sputum samples from cystic fibrosis patients during antipseudomonal treatment.

The in vivo activity and source of beta-lactamase in sputum samples from 43 patients with cystic fibrosis (CF) during a 2-week antipseudomonal treatment were studied. A colorimetric method, based on the conversion of nitrocefin, was used for quantitation of the sputum beta-lactamase activity. beta-Lactamases in sputum were characterized by isoelectric focusing and inhibition profile and were co...

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Utility of gram staining for evaluation of the quality of cystic fibrosis sputum samples.

The microscopic examination of Gram-stained sputum specimens is very helpful in the evaluation of patients with community-acquired pneumonia and has also been recommended for use in cystic fibrosis (CF) patients. This study was undertaken to evaluate that recommendation. One hundred one sputum samples from CF patients were cultured for gram-negative bacilli and examined by Gram staining for bot...

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2009

ISSN: 1569-1993

DOI: 10.1016/s1569-1993(09)60244-7