Clinical Trial Results: Sharing Results, Speeding Discoveries

Interpretation of clinical trial results

Evidence from clinical trials is fundamental to ethical medical practice. Along with patient preferences, circumstances, and clinical experience, it is central to effective clinical decision-making. Applying evidence to clinical questions requires filtering in the form of three questions: first, do the trial results reflect true effects of intervention, rather than artifactual ones (validity)? ...

Is withholding clinical trial results "research misconduct"?

Publishing Clinical Trial Results: The Future Beckons

250–500 words Variable Specialists (clinicians and researchers) Low Usually (IMRAD structure) No External review (accept/reject) but no chance to revise ICH E3 summary 2–3,000 words Only if posted by company Regulators Low Yes Weak Extensive internal and some external (investigators)

Communicating clinical trial results to research participants.

BACKGROUND Communicating clinical trial results to research participants is seldom accomplished in a timely or an effective manner. OBJECTIVE To evaluate the effectiveness of a plan to communicate results in an industry-sponsored randomized controlled trial for Huntington disease. DESIGN, SETTING, AND PARTICIPANTS Postal survey to research participants at 28 of 41 research sites (including ...

Sharing Results with Clinical Trial Participants: Insights from an Online Survey of Chinese Consumers.

To the Editor: Clinical trial participants have a right to know the results from the trials that they enable.[1] European and North American research, however, shows that trial results are rarely shared with participants.[2] Given the increase in industry‐sponsored trials in China, we conducted the first investigation into Chinese consumer views about sharing the clinical trial results with par...