Clinical Significance of Complement Deficiencies

Complement in human diseases: Lessons from complement deficiencies.

Complement deficient cases reported in the second half of the last century have been of great help in defining the role of complement in host defence. Surveys of the deficient individuals have been instrumental in the recognition of the clinical consequences of the deficiencies. This review focuses on the analysis of the diseases associated with the deficiencies of the various components and re...

Expression and clinical significance of complement C3, complement C4b1 and apolipoprotein E in pancreatic cancer

Pancreatic cancer (PC) remains a devastating disease with a five-year survival rate of <5%. The difficulty in making an early diagnosis and the frequent occurrence of metastasis are important reasons for this poor prognosis. In China, the incidence of PC has been increasing steadily. Therefore, the present study aimed to identify effective markers in the early and advanced stages of PC. The exp...

Inherited Classical and Alternative Pathway Complement Deficiencies in Children: A Single Center Experience

Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach.

Complement deficiencies comprise between 1 and 10% of all primary immunodeficiencies (PIDs) according to national and supranational registries. They are still considered rare and even of less clinical importance. This not only reflects (as in all PIDs) a great lack of awareness among clinicians and general practitioners but is also due to the fact that only few centers worldwide provide a compr...

Hereditary and acquired complement deficiencies in animals and man.

Let's read! We will often find out this sentence everywhere. When still being a kid, mom used to order us to always read, so did the teacher. Some books are fully read in a week and we need the obligation to support reading. What about now? Do you still love reading? Is reading only for you who have obligation? Absolutely not! We here offer you a new book enPDFd hereditary and acquired compleme...