Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

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Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

Laryngeal edema is a frequent complication of intubation. It often presents shortly after extubation as post-extubation stridor and results from damage to the mucosa of the larynx. Mucosal damage is caused by pressure and ischemia resulting in an inflammatory response. Laryngeal edema may compromise the airway necessitating reintubation. Several studies show that a positive cuff leak test combi...

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Postextubation laryngeal edema and stridor resulting in respiratory failure in critically ill adult patients: updated review

Endotracheal intubation is frequently complicated by laryngeal edema, which may present as postextubation stridor or respiratory difficulty or both. Ultimately, postextubation laryngeal edema may result in respiratory failure with subsequent reintubation. Risk factors for postextubation laryngeal edema include female gender, large tube size, and prolonged intubation. Although patients at low ri...

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Neuroventilatory efficiency and extubation readiness in critically ill patients

INTRODUCTION Based on the hypothesis that failure of weaning from mechanical ventilation is caused by respiratory demand exceeding the capacity of the respiratory muscles, we evaluated whether extubation failure could be characterized by increased respiratory drive and impaired efficiency to generate inspiratory pressure and ventilation. METHODS Airway pressure, flow, volume, breathing freque...

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Spontaneous breathing trial and post-extubation work of breathing in morbidly obese critically ill patients

BACKGROUND Predicting whether an obese critically ill patient can be successfully extubated may be specially challenging. Several weaning tests have been described but no physiological study has evaluated the weaning test that would best reflect the post-extubation inspiratory effort. METHODS This was a physiological randomized crossover study in a medical and surgical single-center Intensive...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2009

ISSN: 1364-8535

DOI: 10.1186/cc8142