منابع مشابه
[Clinical overview of neuromyelitis optica].
Neuromyelitis optica (NMO) is a condition characterized by attacks of severe bilateral optic neuritis and myelitis. Historically, the prototypic syndrome was diagnosed only when these symptoms occurred nearly simultaneously as a monophasic illness. However, a contemporary view acknowledges that most commonly this condition is a relapsing disorder characterized by recurrent attacks, usually of u...
متن کاملClinical features of neuromyelitis optica in children
Objective: To compare clinical features of pediatric neuromyelitis optica (NMO) to other pediatric demyelinating diseases. Methods: Review of a prospective multicenter database on children with demyelinating diseases. Case summaries documenting clinical and laboratory features were reviewed by an adjudication panel. Diagnoses were assigned in the following categories: multiple sclerosis (MS), a...
متن کاملNeuromyelitis Optica
An 11-year-old girl developed sudden visual loss in her left eye, preceding subacute myelitis by 9 months. Multifocal lesions in the central nervous system were demonstrated by magnetic resonance imaging. Although unilateral blindness is unusual, the clinical findings predominantly involving the optic nerve and spinal cord were consistent with the diagnosis of neuromyelitis optica (NMO). This c...
متن کاملTreatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate
BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...
متن کاملImmunotherapy of Neuromyelitis Optica
Neuromyelitis optica (NMO) is a chronic inflammatory disease of the central nervous system that affects the optic nerves and spinal cord resulting in visual impairment and myelopathy. There is a growing body of evidence that immunotherapeutic agents targeting T and B cell functions, as well as active elimination of proinflammatory molecules from the peripheral blood circulation, can attenuate d...
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ژورنال
عنوان ژورنال: Rinsho Shinkeigaku
سال: 2009
ISSN: 0009-918X,1882-0654
DOI: 10.5692/clinicalneurol.49.894